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However, 74 genes were altered in both smoke exposure groups and LCs altered 62 unique genes (Fig

Additionally, the intense regime uses larger, longer and deeper puffs. This intense smoking regime is also characterized by a different ISO standard, as of 2018: Of course, no machine smoking regime can reflect the individual variation in nicotine uptake among smokers and heated tobacco product users

It behaves more like a broad mineral bank that releases small amounts over time as water, root acids, and microbes break it down, which is why growers often notice steadier, long-term improvements rather than an overnight growth surge

In this context, there is a clear need for a comprehensive evaluation of all available population-level primary prevention strategies for tobacco control to ascertain and compare their effects on smoking behaviour